Yes, there is a direct train from Barcelona to Madrid. We usually find around 38 direct trains on the route from Barcelona to Madrid every weekday. There are typically fewer trains leaving at weekends, when we found around 30 departures.
Can you take a high-speed train from Barcelona to Madrid?
The 621 km (386 mile) high-speed line from Barcelona to Madrid opened in 2008, and high-speed trains now link Barcelona Sants & Madrid Atocha in as little as 2h30 at up to 310 km/h (193 mph). Before it opened, trains took 7 hours on the classic line.